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AbstractAbstract
[en] Isotopic techniques occupy a leading place amongst examinations practicable on coronary patients because of their reliability and the safety and simplicity of their use. The present work reviews the possible applications of selective coronary scintigraphy in pathology. After a brief discussion on scintigraphy, isotopic techniques for myocardium research, coronarography and other methods to study local myocardium perfusion the theoretical bases for the use of the exploration are studied, the techniques and methods employed are reported and the results discussed. Coronary scintigraphy consists of selective injection in the two coronary arteries previously catheterized during a coronarography, of two different populations of microspheres labelled with two physically short-lived indicators: 15μ 99m Tc-labelled serumalbumin microspheres, 10 to 15μ In-labelled siderophiline microspheres. Various studies have shown the complete harmlessness of the exploration when certain precautions are taken regarding the size and number of the spheres. The microspheres disperse into the downstream arterial territory proportionally to the number of capillaries present in the different parts of the irrigated region, and are temporarily stopped in the precapillaries. The preparation of the different images needed to interpret the Face and OAG examination for the left coronary, then for the right coronary, is carried out at the end of the coronarography and lasts about 45 minutes. It is also possible by selective injection in the aorta-coronary bridges to judge their functional condition by observation of the regions they irrigate. 56 patients of the Necker hospital cardiological clinic have been examined
[fr]
Les techniques isotopiques occupent une place de choix parmi les examens praticables chez le malade coronarien, par leur fiabilite, la securite et la simplicite de leur utilisation. L'objet du present travail est d'exposer les possibilites d'application de la Scintigraphie Coronaire Selective en pathologie. Apres avoir effectue un rappel sur la scintigraphie, les techniques isotopiques d'etude du myocarde, la coronarographie et les autres methodes d'etude de la perfusion myocardique locale, on a etudie les bases theoriques d'utilisation de l'exploration, expose les techniques et methodes employees et discute les resultats. La scintigraphie coronarienne consiste en l'injection selective dans les deux arteres coronaires prealablement catheterisees, au cours d'une coronarographie, de deux populations de microspheres differentes, marquees a l'aide de deux indicateurs de courte periode physique: microspheres de serumalbumine de 15μ marquees au sup(99m)Tc, microspheres de siderophiline de 10 a 15μ marquees a l'In. Differents travaux ont montre l'inocuite totale de l'exploration lorsqu'un certain nombre de precautions est respecte quant a la taille des spheres, leur nombre. Les microspheres vont se distribuer dans le territoire arteriel d'aval de facon proportionnelle au nombre de capillaires presents dans les differentes parties du territoire irrigue, et se bloquer dans les precapillaires momentanement. La realisation des differentes images necessaires a l'interpretation de l'examen Face et OAG pour la coronaire gauche, puis pour la coronaire droite est effectuee a la fin de la coronarographie et dure approximativement 45 minutes. L'exploration permet egalement par l'injection selective dans les pontages aortocoronariens de juger de leur etat fonctionnel par la mise en evidence des territoires irrigues par ceux-ci. 56 malades coronariens de la clinique cardiologique de l'hopital Necker ont ete exploresOriginal Title
Scintigraphie coronaire selective
Primary Subject
Source
1975; 174 p; These (D. Med.).
Record Type
Miscellaneous
Literature Type
Thesis/Dissertation
Report Number
Country of publication
ARTERIES, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BLOOD VESSELS, BODY, CARDIOVASCULAR SYSTEM, COUNTING TECHNIQUES, DIAGNOSTIC TECHNIQUES, GLOBULINS, GLOBULINS-BETA, HOURS LIVING RADIOISOTOPES, INDIUM ISOTOPES, INTERMEDIATE MASS NUCLEI, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, MEDICINE, NUCLEAR MEDICINE, NUCLEI, ODD-EVEN NUCLEI, ORGANIC COMPOUNDS, ORGANS, PROTEINS, RADIOISOTOPE SCANNING, RADIOISOTOPES, STABLE ISOTOPES, TECHNETIUM ISOTOPES, YEARS LIVING RADIOISOTOPES
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