[en] Instrumentation and methods described were used for a Department of Energy (DOE) sponsored, high-sensitivity, aerial gamma-ray spectrometer and magnetometer survey of Dyersburg (Kentucky, Missouri, Tennessee); Paducah (Indiana, Illinois, Kentucky, MIssouri); Poplar Bluff (Arkansas, Missouri); and Rolla (Missouri) NTMS, 1:250,000-scale quadrangle. The objective of the work was to define areas showing surface indications of a generally higher uranium content where detailed exploration for uranium would most likely be successful. A DC-3 aircraft equipped with a high-sensitivity gamma-ray spectrometer and ancillary geophysical and electronic equipment was employed for each quadrangle. The system was calibrated using the DOE calibration facilities at Grand Junction, Colorado, and Lake Mead, Arizona. Gamma-ray spectrometric data were processed to correct for variations in atmospheric, flight, and instrument conditions and were statistically evaluated to remove the effects of surface geologic variations. The resulting first-priority uranium anomalies (showing simultaneously valid eU, eU/eTh, and eU/K anomalies) were interpreted to evaluate their origin and significance. Results of the interpretation in the form of a preferred-anomaly map, along with significance-factor profile maps, stacked profiles, histograms, and descriptions of the geology and known uranium occurrences are presented in Volume 2 of this final report