[en] This report summarizes work carried out at the Nuclear Physics Laboratory of the University of Colorado from November 1, 1978 to October 31, 1979, under contract EY-76-C-02-0535.A003 between the University of Colorado and the United States Department of Energy. Experimental studies of light ion-induced reactions were performed with the AVF cyclotron, which continues each year to produce beams of yet higher quality. Charged-particle studies continued to emphasize use of the high-resolution spectrometer system, but some return to broad-range spectroscopic studies using solid state detectors also occurred. Neutron time-of-flight experiments used 9-meter and 30-meter flight paths. Neutron-gamma ray coincidence studies developed into a new and promising field. The new PDP 11/34 data acquisition system was of great value in allowing such multiparameter experiments. Smaller programs in nuclear astrophysics, plasma diagnostic development, and medical physics were also undertaken. Research activities based at other accelerators grew. Studies of future directions for light-ion accelerators, including work on intense pulsed ion sources, orbit dynamics, and storage rings, were greatly enlarged. 19 of the articles in this report were abstracted and indexed individually. Lists of publications and personnel conclude this report