[en] Some regularities of the external irradiation action on the receptor apparatus of T-lymphocytes mediating their homing in the peripheral lymph nodes, were studied in experiments on mice CBA. Irradiation effect inhibited the action of concanavalin A and trypsin on the lymphocytes distribution. Suppression of primary and secondary T-lymphocytes migration into the lymph nodes, induced by irradiation, had a distinctly dose-dependent character, and was more stable than migration disturbances resulting from the concavalin A or trypsin lymphocytes treatment, this pointing to marked radiation injury of the lymphocytes receptors