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AbstractAbstract
[en] Administration of [14C]clorferron in a single oral dose of 0.5 and 20 mg/kg body weight to female rats resulted in a urinary excretion of > 74% of the given dose during the first 24 h. Approx. 8% of the dose was eliminated in faeces within 7 days. 7 days after dosing, very low levels of [14C]chlorferron-derived residues were detected in all analyzed organs. These findings indicated that chlorferron was absorbed from the gastro-intestinal tract in appreciable quantities, but was rapidly excreted mainly via the urine with small amounts only in the faeces. (Auth.)
Primary Subject
Record Type
Journal Article
Journal
Toxicology Letters; ISSN 0378-4274;
; v. 7(6); p. 449-552

Country of publication
ANIMALS, AZINES, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BIOLOGICAL MATERIALS, BIOLOGICAL WASTES, BODY FLUIDS, CARBON ISOTOPES, CLEARANCE, DIGESTIVE SYSTEM, EVEN-EVEN NUCLEI, HETEROCYCLIC COMPOUNDS, HYDROXY COMPOUNDS, ISOTOPES, KINETICS, LIGHT NUCLEI, MAMMALS, NUCLEI, ORGANIC ACIDS, ORGANIC COMPOUNDS, ORGANIC HALOGEN COMPOUNDS, ORGANIC IODINE COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, ORGANIC SULFUR COMPOUNDS, PYRIDINES, QUINOLINES, RADIOISOTOPES, REAGENTS, RODENTS, SULFONIC ACIDS, VERTEBRATES, WASTES, YEARS LIVING RADIOISOTOPES
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