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Bice, D.E.; Harris, D.L.; Brooks, A.L.; Mewhinney, J.A.
Inhalation Toxicology Research Institute. Annual report, October 1, 1979-September 30, 19801980
Inhalation Toxicology Research Institute. Annual report, October 1, 1979-September 30, 19801980
AbstractAbstract
[en] Results of this study indicated that the number of antibody-forming cells in lung-associated lymph nodes after intratracheal immunization was significantly lower in animals exposed to 239PuO2. Only a few antibody-forming cells were found in spleen and cervical lymph nodes. Thus, 239PuO2 exposure suppressed immune responses in lung-associated lymph nodes, although their filtering capacity was unaffected and antigen did not translocate to the spleen. Changes in immunologic responses were observed as the animals aged and the number of antibody-forming cells gradually decreased in the lung-associated lymph nodes and increased in the spleen
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Diel, J.H.; Bice, D.E.; Martinez, B.S. (eds.); Lovelace Biomedical and Environmental Research Inst., Albuquerque, NM (USA); p. 158-161; Dec 1980; p. 158-161
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Report
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ACTINIDE COMPOUNDS, ACTINIDE NUCLEI, ALPHA DECAY RADIOISOTOPES, ANIMALS, BIOLOGICAL EFFECTS, BODY, CHALCOGENIDES, EVEN-ODD NUCLEI, HEAVY NUCLEI, INTAKE, ISOTOPES, KINETICS, LYMPHATIC SYSTEM, NUCLEI, ORGANS, OXIDES, OXYGEN COMPOUNDS, PLUTONIUM COMPOUNDS, PLUTONIUM ISOTOPES, PLUTONIUM OXIDES, RADIATION EFFECTS, RADIOISOTOPES, RESPIRATORY SYSTEM, TRANSURANIUM COMPOUNDS, YEARS LIVING RADIOISOTOPES
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