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AbstractAbstract
[en] The results of different procedures of radiotherapy of 118 patients with locally widespread laryngeal carcinomas are analyzed. 30 of them received a telegamma therapy, 20 a combined radiotherapy, 36 an electron therapy, 32 an electron therapy with synchronization of the tumor cell cycle by 5-fluorourazil. The therapeutic results were evaluated according to the regression extent of the tumor and to the duration of the period without recurrence. The best immediate effect was obtained by electron therapy (55.5 +- 8.3% of patients), in the other groups there was a complete regression of the tumor in 28-33% of the patients. Recurrences developed in the first 3 years in all patient groups with predominance in the first 2 years. A further tumor growth occurred after complete (about 40-54% of patients) as well as after partial regression of the tumor (about 78-86%). All groups showed the same late results independently of the method of treatment: 5 years and more 27.8-29.3% of the patients are living without recurrences. Radiation responses of the skin and of the mucosa developed significantly more seldom in electron and combined therapy. (author)
Original Title
Vergleichende Analyse der strahlentherapeutischen Ergebnisse bei lokal weitausgedehnten Larynxkarzinomen
Primary Subject
Record Type
Journal Article
Journal
Radiobiologia Radiotherapia; ISSN 0033-8184;
; v. 22(1); p. 25-31

Country of publication
ANTIMETABOLITES, ANTIMITOTIC DRUGS, AZINES, BEAMS, DISEASES, DRUGS, ELECTROMAGNETIC RADIATION, HETEROCYCLIC COMPOUNDS, HYDROXY COMPOUNDS, IONIZING RADIATIONS, LEPTON BEAMS, MEDICINE, NEOPLASMS, ORGANIC COMPOUNDS, ORGANIC FLUORINE COMPOUNDS, ORGANIC HALOGEN COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, PARTICLE BEAMS, PYRIMIDINES, RADIATIONS, RESPIRATORY SYSTEM, THERAPY, URACILS
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