[en] Selected topics illustrate results obtained at CERN, mostly during the first half of 1981. The report deals first with the development of facilities for antiproton accumulation and acceleration, and for colliding beams of antiprotons and protons. Other developments of accelerators and of particle detectors are also presented. An outline is then given of the current understanding of the constituents of matter and of the forces acting between them. This framework is used for the presentation of CERN's experimental results. The topics covered include tests of the quark-parton model, properties of the new particles containing charm or beauty quarks, studies of the structure of the nucleon, tests of quantum chromodynamics (QCD), and investigations of the weak interaction. (orig.)