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AbstractAbstract
[en] The major objective of this project is to determine dose-effect relationships of inhaled plutonium nitrate in dogs to aid in the prediction of health effects of accidental exposure in man. For lifespan dose-effect studies, beagle dogs were given a single inhalation exposure to 239Pu(NO3)4, in 1976 and 1977. The earliest biological effect was on the hematopoietic system; as described in previous Annual Reports, lymphopenia and neutropenia occurred at the two highest dose levels. Radiation pneumonitis, lung cancer, and bone cancer have been observed at the highest dose levels
Primary Subject
Source
Drucker, H.; Pacific Northwest Lab., Richland, WA (USA); p. 73-76; Feb 1982; p. 73-76; Available from NTIS., PC A10/MF A01 as DE82011457
Record Type
Report
Report Number
Country of publication
ACTINIDE COMPOUNDS, ACTINIDE NUCLEI, ALPHA DECAY RADIOISOTOPES, ANIMALS, BIOLOGICAL EFFECTS, BIOLOGICAL RADIATION EFFECTS, BODY, DIGESTIVE SYSTEM, DISEASES, DOGS, EVEN-ODD NUCLEI, GLANDS, HEAVY NUCLEI, HEMIC DISEASES, INTAKE, ISOTOPES, KINETICS, LEUKOPENIA, MAMMALS, NITRATES, NITROGEN COMPOUNDS, NUCLEI, ORGANS, OXYGEN COMPOUNDS, PATHOLOGICAL CHANGES, PLUTONIUM COMPOUNDS, PLUTONIUM ISOTOPES, RADIOISOTOPES, RESPIRATORY SYSTEM, SYMPTOMS, TRANSURANIUM COMPOUNDS, VERTEBRATES, YEARS LIVING RADIOISOTOPES
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