[en] The Banha lectin extracted from a Korean native plant (Pinellia ternata) has known to be a hemagglutinating protain, and its purification and characterization were reported. As Banha lectin is a potential tumor localizing agent in considering its characteristics, in-vitro and in-vivo experimental studies have been carried out using sup(99m)Tc-labelled Banha lectin. The specific activities of Banha lectin and sup(99m)Tc-labelled Banha lectin on erythrocytes of rabbit, mouse, rat, and Sarcoma-180 tumor cell were 1,062 HU, 133 HU, 66 HU, and 66 HU, respectively. Activity of lectin were not changed by labelling with sup(99m)Tc, and Sarcoma-18O tumor cell and erythrocytes of rat had some extent of affinity for the lectin. The biologic distribution of sup(99m)Tc-labelled Banha lectin in tumor-bearing mice transplanted with Sarcoma-180 after intravenous injection appeared in the order of; kidney (11.66%), liver (6.80%), tumor (0.66%), blood (0.65%), lung (0.53%), spleen (0.44%), pancreas (0.26%), stomach (0.19%) at 1 hr after injection, and appeared in the order of; kidney (4.30%), liver (0.31%), tumor (0.29%) at 24 hrs after injection, respectively. The concentration of Banha lectin in blood decreased rapidly and it was accumulated slightly more at tumor than at other organs expect kidney and liver. There-fore, the sup(99m)Tc-labelled Banha lectin is expected to be applicable as a tumor localizing agent. (Author)