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Waxweiler, R.J.; Archer, V.E.; Roscoe, R.J.; Watanabe, A.; Thun, M.J.
Epidemiology applied to health physics1983
Epidemiology applied to health physics1983
AbstractAbstract
[en] The long-term health effects associated with the milling of uranium ore are of interest particularly because of exposures to uranium and thorium-230. Excess risks of pulmonary and lymphatic malignancies have been suggested by previous epdiemiologic studies of persons milling or smelting uranium ores, and nephrotoxic effects of uranium have been reported in both man and animals. To test these three previously reported associations and to assess all cause-specific mortality patterns among uranium mill workers, we carried out a retrospective cohort study of 2002 uranium millers employed in any of seven mills at least one year before 1972. Ninety-eight percent (98%) followup of the cohort through 1977 resulted in 533 deaths observed versus 605 expected from US White male mortality rates. Mortality from most causes was lower than expected. Significant excess risks were found only for nonmalignant respiratory disease and miscellaneous accidents but not for any of the three diseases of a priori interest. However, nonsignificant excesses were found for lymphatic malignancies after 20 years latency and for death due to chronic nephritis among short-term workers
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Inhalation Toxicology Research Inst., Albuquerque, NM (USA); Sandia National Labs., Albuquerque, NM (USA); Los Alamos National Lab., NM (USA); USDOE, Washington, DC; p. 428-435; 1983; p. 428-435; Epidemiology applied to health physics conference; Albuquerque, NM (USA); 10-14 Jan 1983; Available from NTIS, PC A24/MF A01; 1 as DE83014383
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