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AbstractAbstract
[en] The present invention discloses the effect of ultraviolet (UV) radiation on platelet concentrates collected in a plastic container, particularly in a polypropylene bag. Samples irradiated at 310 mm for 30 minutes at a dose of 774 J/M2 show no loss of platelet function as determined by ADP, collagen, or ristocetin-induced aggregation. Lymphocytes isolated from irradiated units are unable to act as responders or stimulators in a mixed lymphocyte reaction. The invention provides a device and a method of UV irradiation of platelet concentrates resulting in transfusible cell suspention unable to evoke immunological response while retaining normal platelet function
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10 Jun 1986; 31 Jan 1985; 22 p; ZA PATENT DOCUMENT 85/8940/A/; US PRIORITY 696,657; Available from Patents Office, Private Bag X400, Pretoria, 0001, South Africa; Priority date: 31 Jan 1985
Record Type
Patent
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