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AbstractAbstract
[en] Human platelets were labelled with aqueous 111In-tropolonate in comparison with 111In-oxinate. In normals the labelling efficiency with 111In-tropolonate was higher (93%±2%) than with 111In-oxinate (67%±8%) (P<0.05). In cases of severe thrombocytopenia, lower labelling efficiencies were obtained. In six normals a mean platelet life of 9 days ± 3 days and an initial recovery of 59%±15% were obtained. In twelve patients with trombocytopenia the mean platelet life was 4 days ± 4 days and the initial recovery was 58%±20%. The absolute uptake of radioactivity in spleen and in liver in both groups are reported. (orig.)
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ANIMALS, AZINES, BETA DECAY RADIOISOTOPES, BIOLOGICAL MATERIALS, BLOOD, BLOOD CELLS, BODY, BODY FLUIDS, COUNTING TECHNIQUES, DAYS LIVING RADIOISOTOPES, DIAGNOSTIC TECHNIQUES, DIGESTIVE SYSTEM, DISEASES, DRUGS, ELECTRON CAPTURE RADIOISOTOPES, EVALUATION, GLANDS, HETEROCYCLIC COMPOUNDS, HYDROXY COMPOUNDS, INDIUM ISOTOPES, INTERMEDIATE MASS NUCLEI, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LABELLED COMPOUNDS, MAMMALS, MATERIALS, MINUTES LIVING RADIOISOTOPES, NUCLEI, ODD-EVEN NUCLEI, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, ORGANS, PRIMATES, PYRIDINES, QUINOLINES, RADIOACTIVE MATERIALS, RADIOISOTOPE SCANNING, RADIOISOTOPES, VERTEBRATES
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