[en] This circular has been prepared in response to numerous requests for information regarding routes for the shipment of irradiated reactor (spent) fuel subject to regulation by the Nuclear Regulatory Commission (NRC). The NRC staff approves such routes prior to their use, in accordance with the regulatory provisions of 10 CFR Part 73.37. The objective of the safeguards regulations contained in 10 CFR Part 73.37 is to provide protection against radioactive dispersal caused by malevolent acts by persons. The design and construction of the casks used to ship the spent fuel provide adequate radiological protection of the public health and safety against accidents. Therfore, transporting appropriately packaged spent fuel over existing rail systems and via any highway system is radiologically safe without specific NRC approval of the route. However, to assure adequate planning for protection against actual or attempted acts of radiological sabotage, the NRC requires advance route approval. This approval is given on a shipment-by-shipment or series basis, it is not general approval of the route for subsequent spent fuel shipments. Spent fuel shipment routes, primarily for road transportation, but also including three rail routes, are indicated on reproductions of road maps. Also included are the amounts of material shipped during the approximate 8-year period that safeguards regulations have been effective. This information is current as of September 30, 1987