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Cross, F.T.; Palmer, R.F.; Busch, R.H.; Dagle, G.E.; Filipy, R.E.; Ragan, H.A.
Life-span radiation effects studies in animals: What can they tell us: DOE symposium series 581986
Life-span radiation effects studies in animals: What can they tell us: DOE symposium series 581986
AbstractAbstract
[en] Biological effects observed in dogs and rodents after the inhalation of radon and radon daughters have included, primarily, respiratory carcinoma, pulmonary fibrosis, emphysema, and life-span shortening. Extrapulmonary lesions observed are not considered significant except for certain hematological effects. In this paper we present biological effects data resulting from chronic exposures of hamsters, rats, and beagle dogs. Emphasis is placed on the carcinogenic effects of radon and radon daughters, including the influences of radon-daughter exposure rate, unattachment fraction, and disequilibrium and of concomitant exposure to other pollutants. These data are correlated with results from human epidemiological studies. Plausible values for the radon (radon-daughter) lifetime lung-cancer risk coefficient are provided. 30 refs., 3 tabs
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Thompson, R.C.; Mahaffey, J.A. (eds.); Pacific Northwest Lab., Richland, WA (USA); p. 608-623; Oct 1986; p. 608-623; 22. Hanford life sciences symposium - life-span radiation effects studies in animals - what can they tell us; Richland, WA (USA); 27-29 Sep 1983; Available from NTIS, PC A99; 3 as TI87000490
Record Type
Report
Literature Type
Conference
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BEAGLES, BIOLOGICAL RADIATION EFFECTS, CARCINOMAS, DAUGHTER PRODUCTS, DOSE-RESPONSE RELATIONSHIPS, EMPHYSEMA, EPIDEMIOLOGY, EXTRAPOLATION, HAMSTERS, INHALATION, LIFE SPAN, LUNGS, MAN, MORTALITY, RADIATION EFFECTS, RADIOACTIVE AEROSOLS, RADON, RATS, RESPONSE MODIFYING FACTORS, RISK ASSESSMENT, SURVIVAL TIME, TOBACCO SMOKES
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