[en] The waste-handling building (WHB) at the Yucca Mountain repository is a reinforced concrete structure with massive shear walls whose thicknesses are established by shielding requirements. The probabilities of seismic damage to the WHB are calculated in this paper. To determine these probabilities seismic hazard curves for the site and fragility curves for the building were developed and combined. The details of this work are found in SNL (1988). The seismic hazard analysis considers both ground acceleration at the WHB site and vertical ground rupture under the WHB. Standard methods (McGuire, 1976; 1978) were used to estimate the acceleration hazard assuming that there is not ground rupture under the WHB. The ground rupture hazard from unknown faults was estimated using a conservative approach developed in this study. The acceleration hazard associated with ground rupture under the WHB was also computed. 7 refs., 16 figs