[en] A decision-making methodology is presented that combines systems and risk analysis techniques to evaluate hazardous waste management practices associated with DOE weapon production operations. The methodology provides a systematic approach to examining waste generation and waste handling practices in addition to the more visible disposal practices. Release-exposure scenarios for hazardous waste operations are identified and operational risk is determined. Comparisons may be made between existing and alternative waste management practices (and processes) on the basis of overall risk, cost and compliance with regulations. Managers can use this methodology to make and defend resource allocation decisions and to prioritize research needs