[en] The need to prepare specifically radiohalogenated organic compounds rapidly and in high specific activity has stimulated the evaluation of organometallics to achieve this objective. The versatility associated with the preparation of organotin intermediates and their ability to be transformed to the corresponding radiohalogenated derivatives has made them extremely useful in the preparation of a variety of radiodiagnostic and radiotherapeutic agents. The preparation of alkenyl and aryl trialkyl stannanes is reviewed as well as their conversion to radiofluorinated, brominated, iodinated and astatinated products