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Basha, S.G.; Krasavin, E.A.; Kozubek, S.
Joint Inst. for Nuclear Research, Dubna (Russian Federation). Lab. of Nuclear Problems1991
Joint Inst. for Nuclear Research, Dubna (Russian Federation). Lab. of Nuclear Problems1991
AbstractAbstract
[en] Inactivation and mutagenesis were studied in Salmonella tester strains after γ-irradiation and after heavy ion irradiation in the presence of glycerol and cysteamine. Bacterial cells were irradiated at Dubna, JINR. Ions from deuterons to carbon were used with residual energies 2-9 MeV/u. The protective effect of glycerol was found both for γ-radiation and for heavy ions up to 50 keV/μm for both cell inactivation and mutagenesis in Salmonella tester strains with different mutation events. Cell sensitivity slightly increased with LET before falling down. The maximum was shifted in the presence of glycerol to the left and was less pronounced. The radioprotective effect of glycerol diminished gradually with LET from 2.0 for γ-radiation to 1.1 for carbon ions. Mutagenesis increases with LET in TA100 strain; in TA98 strain no marked increase could be detected. 13 refs.; 4 figs.; 5 tabs
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1991; 10 p; Submitted to Mutat. Res.
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Report
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ALCOHOLS, AMINES, BACTERIA, BIOLOGICAL EFFECTS, CHARGED PARTICLES, DRUGS, ELECTROMAGNETIC RADIATION, ENERGY TRANSFER, HYDROXY COMPOUNDS, IONIZING RADIATIONS, IONS, MICROORGANISMS, ORGANIC COMPOUNDS, ORGANIC SULFUR COMPOUNDS, RADIATION EFFECTS, RADIATIONS, RADIOPROTECTIVE SUBSTANCES, RESPONSE MODIFYING FACTORS, THIOLS
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