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AbstractAbstract
[en] The effect of chlorophyllin on gamma radiation induced Sister chromatid exchanges (SCE) and on the mitotic index (IM) and average generation time was determined. Groups of mice were treated in one of the following regimens: (1) untreated, (2) treated with chlorophyllin only, (3) irradiated and (4) treated with chlorophyllin and irradiated intraperitoneal administration of chlorophyllin preceding gamma radiation exposure protected again SCE induction and diminution of IM. However, radioprotection was not reflected in the average generation time for the chlorophyllin per se acceleration the average generation time. The results suggest that, under the experimental conditions of the study the SCE and IM are caused by free radicals produced by radiation and wat the action mechanics of chlorophyllin is scavenger free radicals. (Author)
Original Title
Efecto de la clorofilina sobre las frecuencias radio inducidas de intercambios entre cromatidas hermanas (ICH) y de otros eventos citogeneticos en celulas de la medula osea de raton In Vivo
Primary Subject
Source
1992; 106 p; Thesis (Biologist).
Record Type
Miscellaneous
Report Number
Country of publication
ANIMAL CELLS, ANIMALS, BIOLOGICAL EFFECTS, BIOLOGICAL RADIATION EFFECTS, CARBOXYLIC ACIDS, CONNECTIVE TISSUE CELLS, DISEASES, DRUGS, ELECTROMAGNETIC RADIATION, ENERGY TRANSFER, HETEROCYCLIC ACIDS, HETEROCYCLIC COMPOUNDS, INJURIES, IONIZING RADIATIONS, MAMMALS, MUTATIONS, OPTICAL PROPERTIES, ORGANIC ACIDS, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, PHYSICAL PROPERTIES, PHYTOCHROMES, PIGMENTS, PORPHYRINS, RADIATION EFFECTS, RADIATIONS, RESPONSE MODIFYING FACTORS, RODENTS, SOMATIC CELLS, VERTEBRATES
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