[en] This paper states the development laws of regional geological structure of South China and its controlling effect on uranium deposit evolution, and the characteristics of rich uranium formation in different periods of geology-history are analysed. It also discusses the relationship between the distribution of time and space and tectonic structure and environmental vicissitudes. The rock-magma activities-the strong formation of the Diwa Era is of great significance to the formation of uranium deposits within the region, especially to the formation of a series of multi-genesis polygene uranium deposits which are a potential direction in which to look for minerals within the region