[en] Exercise myocardial SPECT using ^99mTc-Teboroxime was performed and the regions of ischemic area were compared with ²⁰¹Tl myocardial SPECT in 8 patients with coronary artery disease. All patients had no evidence of previous myocardial infarction, and underwent bicycle ergometer exercise protocol. At peak exercise, 555 MBq ^99mTc-Teboroxime or 75 MBq ²⁰¹Tl was injected intravenously. After treatment of exercise, images were obtained with a gamma camera rotating through a 180deg arc from 45deg right anterior oblique to 45deg left posterior oblique. The concordance of ^99mTc-Teboroxime SPECT and ²⁰¹Tl SPECT was 63% in ischemic region and 83% in normal region. Furthermore, one patient underwent dipyridamole infusion and ^99mTc-Teboroxime SPECT was carried out. The images obtained by dipyridamole ^99mTc-Teboroxime SPECT were equivalent to the images of exercise ²⁰¹Tl SPECT. ^99mTc-Teboroxime SPECT seems useful for the detection of the coronary artery disease. It was suggested that the evaluation of myocardial viability in acute phase of myocardial infarction can be possible by using ^99mTc-Teboroxime SPECT. (author)