[en] The Plutonium-Uranium Extraction (PUREX) facility at the Hanford Site is a remote canyon facility that began operations in 1956 to support the Atomic Energy Commission and later the Department of Energy in the recovery of plutonium, uranium, and neptunium from spent reactor fuel. This report follows the transition of the PUREX facility from standby mode in 1990 to shutdown/terminal cleanout. Preparation of the Final Safety Analysis Report (FSAR), evaluation of OSR requirements, and the use of the USQ to successfully complete the deactivation of the facility in a timely and cost effective manner are discussed. The major activities, both administrative and procedural, performed as part of the PUREX facility deactivation are described