Filters
Results 1 - 1 of 1
Results 1 - 1 of 1.
Search took: 0.018 seconds
AbstractAbstract
[en] The authors investigated standard SPECT techniques (rotating gamma cameras, multi-hole collimators, and filtered backprojection reconstruction) for imaging α-emitting astatine-211 distributions. The capability of imaging this nuclide would allow in vivo evaluation of the distribution and stability of potential 211At-labelled radiotherapeutic agents. 211At decay yields x-rays in the 77-92 keV range and 500-900 keV gamma rays. This study evaluates the feasibility of SPECT imaging using the x-ray emissions of 211At. Several collimators were evaluated with the determination that the medium-energy collimators used are suitable, with 7% penetration (uncollimated counts versus collimated counts). Several phantoms were imaged and attenuation coefficients measured (narrow-beam μ = 0.182 cm-1 for 77-80 keV x-rays in water). Reconstructed images demonstrate qualitative capabilities and a simple study demonstrates good correction for attenuation and scatter. (author)
Primary Subject
Record Type
Journal Article
Journal
Country of publication
ALPHA DECAY RADIOISOTOPES, ASTATINE ISOTOPES, BETA DECAY RADIOISOTOPES, CHARGED PARTICLES, COMPUTERIZED TOMOGRAPHY, DISTRIBUTION, DRUGS, ELECTROMAGNETIC RADIATION, ELECTRON CAPTURE RADIOISOTOPES, EMISSION COMPUTED TOMOGRAPHY, HEAVY NUCLEI, HELIUM IONS, HOURS LIVING RADIOISOTOPES, IONIZING RADIATIONS, IONS, ISOTOPES, MATERIALS, MEDICINE, NUCLEI, ODD-EVEN NUCLEI, RADIATION DOSE DISTRIBUTIONS, RADIATIONS, RADIOACTIVE MATERIALS, RADIOISOTOPES, SPATIAL DISTRIBUTION, THERAPY, TOMOGRAPHY
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue