[en] With the rapidly changing missions throughout the US Department of Energy (DOE) complex, organizations must be prepared to quickly cope with safety analysis requirements far more sophisticated and voluminous than just a few short years ago. The Savannah River Site (SRS), operated for the DOE by the Westinghouse Savannah River Company, has been a pioneer in the development of methods required to perform quantitative risk assessments for a wide variety of facilities in a cost-effective manner. Industrial, nuclear, and chemical hazards are analyzed. The process begins with the identification of the hazards and continues with the accidents that result in releasing the hazard to a recipient, quantification of the frequency and consequence, and finally determination of the risks. These risk assessments provide the basis for hazards classification of facilities that govern design requirements for structures and equipment, safety analysis reports that define the accident risks that are compared to acceptance criteria, and technical safety requirements that describe the operating envelope to ensure that no undue risk is imposed on the operators or the general public