[en] The synthesis of [1,5'-3H2]naltrindole with labels at both the morphine skeleton and the indole moiety was carried out by catalytic tritiodehalogenation of 1,5'-dibromonaltrindole resulting in a specific activity of 46.1 Ci/mmol (1705 GBq/mmol). The brominated precursor was prepared by the Fischer indole synthesis starting from 1-bromonaltrexone and (4-bromophenyl)hydrazine. (author) 9 figs., 11 refs