[en] Based on the assumption that galactic cosmic ray (GCR) is produced by the diffusive shock wave acceleration of supernova explosion in the Galaxy, the authors simulate the propagation of GCR nuclei in the interstellar medium by using the Monte Carlo method. In the simulating calculation, the authors use the nuclear interaction cross sections and the probabilities of nuclear fragmentation measured in the accelerator experiments; the authors consider the ionization energy loss of GCR nuclei in the standard leaky box model and the effect of solar modulation on the GCR nuclei by using force-field approximation. The calculated B/C, V/Fe and the spectra of O and Fe can be compared with experimental data. Finally, the effects of different compress ratios of shock wave on the calculation results are discussed