[en] The scientific programme based on the Synchrotron Radiation Source (SRS) has continued in 1993/94 to be at the centre of the Daresbury Laboratory's work. The wide range of research in materials and surface science, atomic and molecular physics, chemistry and structural and molecular biology using SRS includes: the interaction between the proteins actin and gelsolin which has relevance to genetic disease; the crystallinity of polythene; the epitaxial growth of lattice-mismatched semi-conducting material systems; cell uptake of molecules by receptor-mediated endocytosis; the crystal structure of copper-palladium alloys; the kinetics of intercalation and its application to molecular electronics; the crystal structure of the minerals antigorite and chrysotile; the development of experimental facilities to allow surface studies of catalytic processes. Major upgrades and improvements in the SRS are also reported. Highlights of the continuing successful use of parallel supercomputers and distributed computing in the collaborative research undertaken by the Theory, Computational Science and Computing group are presented. These range over applications to pharmaceuticals, plasma and ionization on processes, crystal structures of organic molecules and magnetic storage media. (UK)