[en] This is the sixteenth in a series of semiannual technical progress reports on fusion reactor materials. This report combines research and development activities which were previously reported separately. These activities are concerned principally with the effects of the neutronic and chemical environment on the properties and performance of reactor materials; together they form one element of the overall materials programs being conducted in support of the Magnetic Fusion Energy Program of the US Department of Energy. The other major element of the program is concerned with the interactions between reactor materials and the plasma and is reported separately. This report is divided into the following areas: (1) irradiation facilities, test matrices, and experimental methods; (2) dosimetry, damage parameters, transmutation, and activation calculations; (3) materials engineering and design requirements; (4) fundamental mechanical behavior; (5) radiation effects, mechanistic studies, theory and modelings; (6) development of structural alloys; (7) solid breeding materials and beryllium; and (8) ceramics. Selected papers were indexed separately for inclusion in the Energy Science and Technology Database