[en] The three-dimensional structures of macromolecules under static and dynamic conditions are very important for the study of molecular biology. X-ray crystallography is the most powerful tool to obtain the three-dimensional structures of the macromolecules of especially large size, for which synchrotron radiation X-ray is used, The collection of diffraction data is the first, most important step for crystalline structure analysis. Efforts have been exerted to establish the data collection system using monochromatic synchrotron radiation X-ray (SRX). The diffraction intensity data collection system combined with a newly developed Weissenberg camera for macromolecules and an image plate (IP) using SRX has been established at the Photon Factory. Many important biological structures by high resolution have already come out with this data collection system, which is used also for the study on enzymatic reaction mechanism. A time resolved Laue camera has been designed, and the preliminary experiment has been carried out in the Photon Factory. These systems are reported. (K.I.)