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AbstractAbstract
[en] Technetium-99 m-N-(3-bromo-2,4,6-trimethyl acetanilide) iminodiacetic acid (99mTc-Mebrofenin) has been described as having optimal properties as hepatobiliary radiopharmaceutical. This paper describes the synthesis, radiopharmaceutical preparation and biological distribution of new labeled compound. The biodistribution study of 99mTc-Mebrofenin- was carried out in normal mice. The specificity for hepatobiliary excretion blood clearance and cumulative biliary excretion were evaluated in normal and cirrhotic rats. (author). 5 refs, 3 figs, 3 tabs
Source
Associacao Brasileira de Energia Nuclear, Rio de Janeiro, RJ (Brazil); 356 p; 1994; p. 909-911; 5. General Congress on Nuclear Energy; Rio de Janeiro, RJ (Brazil); 28 Aug - 2 Sep 1994; Available from the Library of Comissao Nacional de Energia Nuclear, RJ, BR
Record Type
Miscellaneous
Literature Type
Conference
Country of publication
ANIMALS, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, DRUGS, HOURS LIVING RADIOISOTOPES, INTERMEDIATE MASS NUCLEI, INTERNAL CONVERSION RADIOISOTOPES, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, KINETICS, MAMMALS, MATERIALS, NUCLEI, ODD-EVEN NUCLEI, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, RADIOACTIVE MATERIALS, RADIOISOTOPES, RODENTS, TECHNETIUM ISOTOPES, VERTEBRATES, YEARS LIVING RADIOISOTOPES
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