[en] Instanton calculations in QCD are generically plagued by infrared divergencies associated with the integration over the instanton size ρ. Here, we demonstrate explicitly that the typical inverse hard momentum scale Q^-1 in deep-inelastic scattering provides a dynamical infrared cutoff for the size parameter ρ. Hence, deep-inelastic scattering may be viewed as a distinguished process for studying manifestations of QCD-instantons. For clarity, we restrict the explicit discussion to the simplest chirality-violating process, γ^*+g→q_L+q_R. We calculate the corresponding fixed angle cross-section as well as the contributions to the gluon structure functions, F_2g and F_Lg, within standard instanton perturbation theory in leading semi-classical approximation. To this approximation, fixed-angle scattering processes at high Q² are reliably calculable. In the Bjorken limit, the considered instanton-induced process gives a scaling contribution to F_2g(x,Q²) and the Callan-Gross relation holds. (orig.)