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AbstractAbstract
[en] The development of a national policy for guaranteeing an ample supply of 99mTc to nuclear medicine, involves issues which go beyond the means by which radioactivation is achieved. Indeed, in such an exercise the pragmatic dictates of business and the sensitivities of politics must also be taken into account. Furthermore where a preference towards the nuclear reactor or the potential of cyclotrons is being questioned, the debate is incomplete if the only options that are considered are the fission-based 99Mo generator versus the direct cyclotron production of 99mTc. There is a third option (also neutron γ-based), an alternative to the fission 99Mo generator, which ought not be overlooked. The application of low specific activity (n,γ) 99Mo to a new type of generator, the Gel Generator, has been the focus of much research, particularly in Australia and more recently in China. After the initial concept had been established in the laboratory, the Australian researchers then undertook a comprehensive program of tests on the Gel Generator to assess its potential, either in the clinical laboratory or the centralised radiopharmacy, for supplying 99mTc suitable for nuclear medicine. The outcome of this program was a clear indication that the Gel Generator innovation had the capability to provide both technical and economic advantages to the nuclear medicine industry. These advantages are described. Since that time the Gel Generator has been selected for routine use in China where it now satisfies more than 30% of the 99mTc demand. (author)
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International Atomic Energy Agency, Vienna (Austria); 160 p; ISSN 1011-4289;
; Feb 1999; p. 147-155; 7 refs, 2 figs, 6 tabs

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Report
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ACCELERATORS, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, COLLOIDS, CYCLIC ACCELERATORS, DAYS LIVING RADIOISOTOPES, DISPERSIONS, DRUGS, EVALUATION, EVEN-ODD NUCLEI, HOURS LIVING RADIOISOTOPES, INTERMEDIATE MASS NUCLEI, INTERNAL CONVERSION RADIOISOTOPES, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LABELLED COMPOUNDS, MATERIALS, MOLYBDENUM COMPOUNDS, MOLYBDENUM ISOTOPES, NUCLEI, ODD-EVEN NUCLEI, OXYGEN COMPOUNDS, RADIOACTIVE MATERIALS, RADIOISOTOPES, TECHNETIUM ISOTOPES, TRANSITION ELEMENT COMPOUNDS, YEARS LIVING RADIOISOTOPES
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