[en] The project is devoted to solve ecological and technological goals of Semipalatinsk Nuclear Testing Site and uranium industry of Kazakstan. Its anticipated basic results include: - Creation of common systemic research methodology using the spectral, physical-chemical and biological tests; - Development of new testing methods for molecular-structural variations in water systems; evaluation of effect of water and water systems after radiation irradiation upon physical-chemical and biological properties of subjects, which are contacted with these systems; - Determination of a pattern of interaction between the water and the coarse- and fine-dispersions as well as effect of molecular-structural variations in systems upon physical-chemical and biological processes occurred in these systems; - Determination of water role in radiation-chemical reactions by means of electron, gamma- and ion irradiation of water-mineral model systems. There are following basic goals to be solved to reach a general objective of Project: In Water-Mineralogical Section: - To determine a pattern of interaction between the radiant energy and ion and dispersed (hydrophilic and hydrophobic) components; - To clarify a relationship between physical-chemical properties of water with its isotope composition; - To establish a transfer mechanism of micro dispersed radionuclides in geological and soil conditions of SNTS and a role of water structures in hydrophobic interactions between micro dispersions and non-polar radicals of chemical agents; - To determine the water-molecular structure in acid and alkaline water fractions and interspersion interactions within these fractions; - To establish the interaction with water minerals in ice-like and clathrate-like conditions. - In Biological Section: - To study a role of water structure formation and hydrophobic interactions in the modification of humor immunity components for biological liquids being effected by electron and gamma rays beams; - To study the effect of irradiated water upon a vegetative nervous tonicity, vascular reaction of extremities, and temperature perception as well. - To study the collective cellular reactions in liver and kidneys and the principles of homeostasis support for conditions of irradiated water effect; - To study the hydrophilic and hydrophobic amino acid equilibrium in proteins as a mechanism of genetic code damage due to using of irradiated water. Anticipated results. In the end of this Project following results will be obtained: - A mechanism of non-ion transfer of nuclides by the deep subsurface, subsoil and surface water will be determined, and a role of water-molecular structure in these processes will be studied; - A pattern of water structures organization in phase transition regions will be established; - A method and device for measurement of electric parameters in water systems will be developed; - A relationship between the effect of soluble polymers on water structural states and physical-chemical and rheological properties of systems will be established