Filters
Results 1 - 1 of 1
Results 1 - 1 of 1.
Search took: 0.016 seconds
Kiefer, J.; Egenolf, R.; Ikpeme, S.E.
Recent aspects of cellular and applied radiobiology. Indo-German symposium. Proceedings1999
Recent aspects of cellular and applied radiobiology. Indo-German symposium. Proceedings1999
AbstractAbstract
[en] The induction of DNA double strand breaks (DSB) by different types of ionising radiations was measured in diploid yeast cells using pulsed field electrophoresis. Apart from 80 kV-X-rays and alpha particles a large range of accelerated heavy ions were studied obtained either from GSI, Darmstadt, or HMI, Berlin. Results are reported as induction cross sections, i.e. the probability of a single particle to cause a DSB. Cross sections increase for LET values with ion charge approaching a transient plateau. With heavier ions they increase with ion energy (i.e. with decreasing LET) yielding 'hook' structures. In this regime the action of each ion has to be represented by a separate curve and there is no unique dependence on any physical parameter. The relative biological effectiveness (RBE) is clearly above unity in the LET region between 100 and about 400 keV/μm but falls for higher LET-values. Rejoining of DSB was also measured in a number of selected experiments. For X-rays there seems to be a two-phasic disappearance of DSB with time, with heavy charged particles only the slower component persists. (orig.)
Primary Subject
Source
Schneeweiss, F.H.A. (Forschungszentrum Juelich GmbH (Germany). Inst. fuer Medizin); Sharan, R.N. (North-Eastern Hill Univ., Shillong (India). Dept. of Biochemistry) (eds.); Forschungszentrum Juelich GmbH (Germany). Zentralbibliothek; 180 p; ISBN 3-89336-238-X;
; 1999; p. 108-115; Indo-German symposium on molecular biology of DNA damage and repair; Shillong (India); Apr 1998; ISSN 1433-5581;
; Available from TIB Hannover: RR 1796(30)


Record Type
Miscellaneous
Literature Type
Conference
Country of publication
BIOLOGICAL EFFECTS, BIOLOGICAL RECOVERY, DNA DAMAGES, ELECTROMAGNETIC RADIATION, ENERGY TRANSFER, EUMYCOTA, FUNGI, ION SOURCES, IONIZING RADIATIONS, IRRADIATION, MICROORGANISMS, NUCLEIC ACIDS, ORGANIC COMPOUNDS, PARTICLE SOURCES, PLANTS, RADIATION EFFECTS, RADIATION SOURCES, RADIATIONS, SACCHAROMYCES, YEASTS
Reference NumberReference Number
Related RecordRelated Record
INIS VolumeINIS Volume
INIS IssueINIS Issue