[en] The purpose has been to describe an approach suggested for constructing generalized closure relationships for local and subchannel wall friction, heat and mass transfer coefficients, with not only axial and transversal parameters taken into account, but azimuthal substance transfer effects as well. These constitutive relations that are primary for description of one- and two-phase one-dimensional flow models can be derived from the initial 3-D drift flux formulation. The approach is based on the Reynolds flux, boundary layer and generalized coefficient of substance transfer. One more task has been to illustrate the validity of the 'conformity principle' for the limiting cases. The method proposed is based on the similarity theory, boundary layer model, and a phenomenological description of the regularities of the substance transfer (momentum, heat, and mass), as well as on an adequate simulation of the forms of flow structure by a generalized approach to build (an integrated in form and semi-empirical in maintenance structure) analytical relationships for wall friction, heat and mass transfer coefficients. (author)