[en] Bulk Bi₂Sr₂CaCu₂O_8+δ (Bi2212) bicrystals containing a single high quality [001] twist grain boundary junction were prepared in order to investigate the orbital symmetry of the superconducting order parameter in highly anisotropic Bi-based high temperature superconductors. The misorientation angles of the bicrystals ranged from 0 to 180degree. The microstructure in the vicinity of the junction was characterized using high-resolution, nano-probe analytical microscopy. The authors found that some high angle twist junctions were able to carry a critical current density similar to their constituent single crystals. These results cannot be interpreted in terms of a pure d_x²-_y²-wave order parameter for superconducting Bi2212