[en] Full text: Autologous ⁹⁹Tc^m-leukocyte scanning has been performed in patients for the detection of inflammation, osteomyelitis, query of abscess, infection, fever of unknown origin and cellulitis using gamma camera imaging, in our department at The Royal Melbourne Hospital. Our aim was to demonstrate the effectiveness of the test for an accurate and early diagnosis of the above mentioned diseases. 316 patients were studied (1988-98). Autologous leukocytes were radiolabelled using the manufacturer's instructions (Radpharm). Labelling efficiency >95%. Scans were performed 0.5 and 2-3 h after intravenous administration. The sensitivity of the scan for osteomyelitis was 92%, for abscess 80% and for inflammation 89%. The specificity for osteomyelitis was 90%, for abscess 86% and for inflammation 100%. Results relating to cellulitis and fever of unknown origin have yet to be collated and these will be presented at the conference. In conclusion, the availability, low cost and minimally invasive method of labelling, make the use of ⁹⁹Tc^m-colloid-labelled autologous leukocytes easy and interesting for scintigraphy, especially because no cell separation is involved. During the period of 10 years, no patients suffered any major or minor side-effects from this agent