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AbstractAbstract
[en] Quantitative determination of ppb-order 10B was carried out in a small number of cultured tumor cells by particle tracks by the 10B(n,α)7Li reactions using solid state nuclear track detector (SSNTD) for boron neutron capture therapy research. The detection limit of 10B concentration in tumor cells is less than 1 x 10-3 ppm under our experimental conditions which permits the quantitative determination of 10B in a small number of boronated tumor cells (105/ml = ca. 0.1 mg). Boron quantities in tumor cells determined were well compatible with the tumor cell killing effects of boron neutron capture therapy. (author)
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11 refs.
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Journal Article
Journal
Journal of Radioanalytical and Nuclear Chemistry; ISSN 0236-5731;
; CODEN JRNCDM; v. 247(2); p. 389-392

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ANIMAL CELLS, BARYON REACTIONS, BORON ISOTOPES, CHEMICAL ANALYSIS, HADRON REACTIONS, ISOTOPES, LIGHT NUCLEI, LITHIUM ISOTOPES, MEASURING INSTRUMENTS, MEDICINE, NEUTRON THERAPY, NUCLEAR MEDICINE, NUCLEAR REACTIONS, NUCLEI, NUCLEON REACTIONS, ODD-EVEN NUCLEI, ODD-ODD NUCLEI, RADIATION DETECTORS, RADIOLOGY, RADIOTHERAPY, STABLE ISOTOPES, TARGETS, THERAPY
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