[en] Isotope separation is of great value and traditionally it is achieved by dissipation, which is very complicated and inconvenient. Isotope separation with lasers is quite different from the traditional method, and is expected to give richer isotope yields. The principle of isotope separation with lasers is based on centrifugal force. Generally, when the rotating plasma column is in hydrodynamic equilibrium, the density distribution of different isotope ions is Gaussian along the radial direction, with a larger Gaussian width for ions with larger mass. Consequently, the enrichment along the radial direction radius is different for ions with different mass, thus isotopes with different mass can be separated