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AbstractAbstract
[en] 123I-β-CIT (2β-carbomethoxy-3β-[4-iodophenyl]-tropane), a promising agent for imaging central dopamine transporter, has been successfully used in clinical and differential diagnosis and assessment of the magnitude of degeneration of nigra-striatum in Parkinson's disease. However, due to its poor selectivity for dopamine transporter and prolonged imaging interval (usually 20h after injection), and therefore limits its clinical use. Several new imaging agents have been developed for dopamine transporter in recent years, and significantly improved the characterization for imaging dopamine transporter
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Journal Article
Journal
Foreign Medicine Radiological Medicine and Nuclear Medicine Section; ISSN 1001-098X;
; v. 24(2); p. 62-67

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AMINES, AROMATICS, AUTONOMIC NERVOUS SYSTEM AGENTS, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, CARDIOTONICS, CARDIOVASCULAR AGENTS, COMPUTERIZED TOMOGRAPHY, DIAGNOSTIC TECHNIQUES, DRUGS, ELECTRON CAPTURE RADIOISOTOPES, EMISSION COMPUTED TOMOGRAPHY, FLUORINE ISOTOPES, HOURS LIVING RADIOISOTOPES, HYDROXY COMPOUNDS, INTERMEDIATE MASS NUCLEI, INTERNAL CONVERSION RADIOISOTOPES, IODINE ISOTOPES, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LABELLED COMPOUNDS, LIGHT NUCLEI, MATERIALS, NEUROREGULATORS, NUCLEI, ODD-EVEN NUCLEI, ODD-ODD NUCLEI, ORGANIC COMPOUNDS, PHENOLS, POLYPHENOLS, RADIOACTIVE MATERIALS, RADIOISOTOPES, SYMPATHOMIMETICS, TECHNETIUM ISOTOPES, TOMOGRAPHY, YEARS LIVING RADIOISOTOPES
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