Filters
Results 1 - 1 of 1
Results 1 - 1 of 1.
Search took: 0.017 seconds
Hess, E.; Blessing, G.; Coenen, H.H.; Qaim, S.M., E-mail: s.m.qaim@fz-juelich.de2000
AbstractAbstract
[en] An improved aluminium target system for production of elemental fluorine via the 18O(p,n)18F reaction using a two-step irradiation protocol is described. In the first step highly enriched gaseous oxygen-18 is irradiated with protons to form fluorine-18 which gets deposited on the inner target surface. In the second step, after cryogenic recovery of oxygen-18 target gas, a mixture of elemental 'cold' fluorine and krypton is introduced and a short proton irradiation is done, whereby an isotopic exchange between the gaseous fluorine and the deposited radiofluorine occurs. The second step leads to the recovery of the radiofluorine as [18F]fluorine. Optimisation studies were performed regarding the yield and specific radioactivity of [18F]fluorine. Furthermore, some irradiation parameters relevant to the recovery step were investigated. It was found that a 15 to 20 min irradiation with a beam current of 20 μA is sufficient for the isotopic exchange between the fluorine-carrier and the 18F-radioactivity deposited on the inner wall of the target. The distribution of the 18F-radioactivity deposited on the inner target surface is inhomogeneous, probably due to convection effects. Extensive radioanalytical techniques were applied to characterise the reactivity of [18F]fluorine and to identify undesired nonreactive 18F-compounds, mainly [18F]tetrafluoromethane and [18F]nitrogentrifluoride. The [18F]fluorine produced in the system used has the distinction of having a negligible contamination from those inert 18F-compounds. This is a combined effect of the use of highest purity gases and a welded target construction, which avoids any contact of the gases with organic material during irradiations. The target has proved to be very reliable for production of [18F]fluorine in high yields of up to 34 GBq and specific activities of 350-600 GBq/mmol, both at 30 min after end of activation bombardment
Primary Subject
Source
16 refs., 1 tab., 7 figs. PII: S0969804399002481; Copyright (c) 2000 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: Australia
Record Type
Journal Article
Literature Type
Numerical Data
Journal
Country of publication
ACCELERATOR FACILITIES, ACCELERATORS, BARYON REACTIONS, BETA DECAY RADIOISOTOPES, BETA-PLUS DECAY RADIOISOTOPES, CHARGED-PARTICLE REACTIONS, CURRENTS, CYCLIC ACCELERATORS, DATA, ELEMENTS, FLUIDS, FLUORINE ISOTOPES, GASES, HADRON REACTIONS, HALOGEN COMPOUNDS, HOURS LIVING RADIOISOTOPES, INFORMATION, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, LIGHT NUCLEI, METALS, NONMETALS, NUCLEAR REACTIONS, NUCLEI, NUCLEON REACTIONS, NUMERICAL DATA, ODD-ODD NUCLEI, RADIOISOTOPES, RARE GASES, TARGETS
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue