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AbstractAbstract
[en] A standardised pancake labelled with 20 MBq of 111In Amberlite-resin was used to study colonic transit in spinal-cord-injured subjects. Four methods of presenting the data were assessed in order to determine the best method of presentation for clinical practice. Method: Sixteen subjects (8 tetraplegics, 8 paraplegics), who had sustained traumatic spinal injury at least 12 months prior to the investigation, were studied. Each subject was given a radiolabelled pancake to eat on a Monday, following an overnight fast. Initial anterior and posterior images were acquired at 3-4 hours post ingestion of the pancake and thereafter 3 times daily for a total of 5 days. The colon was divided into 6 regions of interest (ROI) and the counts in each region, for each time point were noted. The counts in each ROI were used to calculate the geometric centre of colonic activity for each time point. The geometric mean (GM) was also calculated from these counts. The percentage activity in each ROI was calculated using the GM. The percentage activity in each ROI was used to construct parametric images, and time-activity curves comparing transit through the right colon with that of the left colon. Visual assessment was made of the analogue images. The agreement between the various methods of analysing the data, for each subject, was compared. Results: There was no complete agreement between the four methods of assessment. The best agreement occurred between the parametric images and the arrival and clearance of activity in the right and left sides of the colon. Conclusion: Visual assessment is subjective. At least two quantitative methods of analysing the data should be used to assess colonic transit
Primary Subject
Source
8. Congress of the World Federation of Nuclear Medicine and Biology; Santiago (Chile); 29 Sep - 2 Oct 2002
Record Type
Journal Article
Literature Type
Conference
Journal
World Journal of Nuclear Medicine; ISSN 1450-1147;
; v. 1(suppl.2); p. 323

Country of publication
BETA DECAY RADIOISOTOPES, BODY, CENTRAL NERVOUS SYSTEM, DAYS LIVING RADIOISOTOPES, DIGESTIVE SYSTEM, DISEASES, ELECTRON CAPTURE RADIOISOTOPES, GASTROINTESTINAL TRACT, INDIUM ISOTOPES, INTERMEDIATE MASS NUCLEI, INTESTINES, ION EXCHANGE MATERIALS, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, MATERIALS, MINUTES LIVING RADIOISOTOPES, NERVOUS SYSTEM, NUCLEI, ODD-EVEN NUCLEI, ORGANS, RADIOISOTOPES
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