[en] In this paper, results of the experimental study of the integrated cross-section of (γ, x)^m (x=n, p, 2n, 3n, α) photonuclear reaction on nuclei with mass numbers 59≤A≤142 in the giant dipole resonance region are presented. Samples of the target materials, either in the form of the element or some simple compound, were irradiated with Bremsstrahlung beam of 25 MeV maximum energy produced by the heavy-current betatron SB-50 of Institute of Applied Physics of National University of Uzbekistan. A device for the intra-chamber Bremsstrahlung irradiation of samples in a betatron, combined with a K5-2A pneumotransport system was used in order to increase the density of the Bremsstrahlung flux was used. The induced activities were examined by detecting and analyzing γ-rays with help of a 40 cm³ Ge(Li) semiconductor spectrometer equipped with a 4096 channel pulse height analyzer. The counting system had a resolution of ∼3 keV for the 1332 keV γ-line of ⁶⁰Co. The yields of photonuclear reactions were obtained by comparing method. The ⁶⁴Cu activities produced by the: ⁶⁵Cu(γ, n)⁶⁴Cu(T_1/2=12.7 h, E_γ=511 keV) processes were used for comparisons. The results were compared with other experimental data. The integrated cross-sections for some reactions are obtained at first