[en] This Paper describes a new methodology for a comprehensive modular Safety Control System (SCS), for a cyclotron site. The developed SCS is a modular approach for controlling the production procedures, safety conditions and documentation aspects in the Cyclotron site. Usually, the safety conditions in cyclotron sites are maintained by a variety of sensors. The cyclotron is supplied from the manufacturer with a self-integrated control system for its operation, yet the comprehensive SCS has to be defined and setup by the customer. Therefore, customers face a lot of integration problems in trying to combine all the signals from the different safety systems such as radiation monitoring, environmental and access control, in order to maintain proper safety working conditions. The presented SCS design provides main user interface and the complete safety solution required by including preset control logic definitions and open logic for specific user applications. The knowledge for the preset control logic definitions was gathered in previous projects. Failure Mode and Effects Analysis (FMEA) method has been implemented on the SCS to analyze the potential failure modes and their impact on the product reliability