Filters
Results 1 - 1 of 1
Results 1 - 1 of 1.
Search took: 0.02 seconds
Snipes, M.B.; Hahn, F.F.; Muggenburg, B.A.; Mauderly, J.L.; McClellan, R.O.; Pickrell, J.A.
Inhalation Toxicology Research Institute annual report 1987-19881988
Inhalation Toxicology Research Institute annual report 1987-19881988
AbstractAbstract
[en] This study was initiated to determine health effects resulting from inhalation of 90Sr in relatively insoluble form. Beagle dogs were briefly exposed by inhalation to produce lung burdens of 90Sr that ranged from 0.12 to 96 μCi (4.4-3500 kBq)/kg body weight. Exposures to the higher concentrations of 90Sr caused radiation pneumonitis and pulmonary fibrosis, typically resulting in death < 500 days after exposure. Exposures to lower concentrations are producing longer term health effects, including cancer of the lung, heart, and tracheobronchial lymph nodes. Most tumors have been hemangiosarcomas. Three 90Sr-exposed dogs were euthanized during the past year. One remaining exposed dog and one control dog are both 14 yr old and are being maintained for lifetime observation. (author)
Primary Subject
Source
Mauderly, J.L.; Mewhinney, J.A.; Bechtold, W.E.; Sun, J.D.; Coons, T.A. (eds.); Inhalation Toxicology Research Institute, Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM (United States). Funding organisation: Office of Health and Environmental Research, U.S. Department of Energy (United States); 659 p; Dec 1988; p. 184-188; 2 figs, 2 tabs
Record Type
Report
Report Number
Country of publication
ALKALINE EARTH ISOTOPES, ANIMALS, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BIOLOGICAL EFFECTS, BODY, CARDIOVASCULAR SYSTEM, DISEASES, DOGS, EVEN-EVEN NUCLEI, INTAKE, INTERMEDIATE MASS NUCLEI, ISOTOPES, KINETICS, LYMPHATIC SYSTEM, MAMMALS, NUCLEI, ORGANS, PATHOLOGICAL CHANGES, RADIATION EFFECTS, RADIOISOTOPES, RESPIRATORY SYSTEM, STRONTIUM ISOTOPES, VERTEBRATES, YEARS LIVING RADIOISOTOPES
Reference NumberReference Number
Related RecordRelated Record
INIS VolumeINIS Volume
INIS IssueINIS Issue