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Manzanares A, E.; Vega C, H.R.; Letechipia de Leon, C.; Guzman E, L.J.; Garcia T, M., E-mail: emanz@cantera.reduaz.mx
Instituto Nacional de Investigaciones Nucleares, Ocoyoacac, Estado de Mexico (Mexico); Comision Nacional de Seguridad Nuclear y Salvaguardias, Mexico D.F. (Mexico); Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico); Comision Federal de Electricidad, Gerencia de Centrales Nucleoelectricas, Mexico D.F. (Mexico)2004
Instituto Nacional de Investigaciones Nucleares, Ocoyoacac, Estado de Mexico (Mexico); Comision Nacional de Seguridad Nuclear y Salvaguardias, Mexico D.F. (Mexico); Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico); Comision Federal de Electricidad, Gerencia de Centrales Nucleoelectricas, Mexico D.F. (Mexico)2004
AbstractAbstract
[en] The purpose of this study was to evaluate the effect of low gamma ray intensity upon Hsp70 expression in human Iymphocytes. The heat shock proteins (Hsp) family, are a group of proteins present in all living organism, therefore there are highly conserved and are related to adaptation and evolution. At cellular level these proteins acts as chaperones correcting denatured proteins. When a stress agent, such heavy metals, UV, heat, etc. is affecting a cell a response to this aggression is triggered only through over expression of Hsp. Several studies has been carried out in which the cellular effect are observed, mostly of these studies uses large doses, but very few studies are related with low doses. Blood of healthy volunteers was obtained and the Iymphocytes were isolated by ficoll- histopaque gradient. Experimental lots were irradiated in a 137 Cs gamma-ray. Hsp70 expression was found since 0.5 c Gy, indicating a threshold to very low doses of gamma rays. (Author)
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2004; 7 p; 15. Annual Congress of the SNM; Cancun (Mexico); 11-14 Jul 2004; pr 22. Annual Meeting of the SMSR; Cancun (Mexico); 11-14 Jul 2004; International Joint Meeting Cancun 2004; Cancun (Mexico); 11-14 Jul 2004; International Conjunct Congress Cancun 2004; Cancun (Mexico); 11-14 Jul 2004; 2004 LAS/ANS Symposium; Cancun (Mexico); 11-14 Jul 2004
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Miscellaneous
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Conference
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ANIMAL CELLS, ANIMALS, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BIOLOGICAL MATERIALS, BLOOD, BLOOD CELLS, BODY, BODY FLUIDS, CESIUM ISOTOPES, CONNECTIVE TISSUE CELLS, DISPERSIONS, DOSES, ELECTROMAGNETIC RADIATION, FEMALE GENITALS, GONADS, HOMOGENEOUS MIXTURES, INFORMATION, INTERMEDIATE MASS NUCLEI, IONIZING RADIATIONS, ISOTOPES, LEUKOCYTES, MAMMALS, MATERIALS, MIXTURES, NUCLEI, ODD-EVEN NUCLEI, ORGANIC COMPOUNDS, ORGANS, PROTEINS, RADIATIONS, RADIOISOTOPES, RODENTS, SEPARATION PROCESSES, SOLUTIONS, SOMATIC CELLS, VERTEBRATES, YEARS LIVING RADIOISOTOPES
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