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Lopez R, V.; Juarez O, C.; Medina L, A.; Perez C, E.; Garcia L, P.
Sociedad Mexicana de Medicina Nuclear A.C., Mexico D.F. (Mexico)2007
Sociedad Mexicana de Medicina Nuclear A.C., Mexico D.F. (Mexico)2007
AbstractAbstract
[en] The general objective of the study was to evaluate the lipidic nanospheres biodistribution charged with cis-diaminedichloroplatinum (II) (cis-DDP) and labelled with radioactive nuclei of Indium-111 (Lip-Cis-in-111) in Wistar rats and in a tumoral model of CaCu. The conclusions were: 1. The system Lip-Cis-in-111 it presents a very fast elimination probably, to a fast recognition response of the reticuloendothelial system (RES). 2. It is planned to make modifications to the formulation to increase the quantity of the hydrophilic polymer (PEG), so that its time of residence in the blood is bigger and allow a bigger accumulation in the tumor. (Author)
Original Title
Estudio de biodistribucion de nanoesferas lipidicas cargadas con cis-diaminodicloroplatino (II) y marcadas con nucleos radioactivos de Indio-111
Primary Subject
Source
2007; 18 p; 41. National Congress of Nuclear Medicine; Mazatlan, Sinaloa (Mexico); 27-30 Apr 2007
Record Type
Miscellaneous
Literature Type
Conference; Numerical Data
Report Number
Country of publication
ANIMALS, BETA DECAY RADIOISOTOPES, COLLOIDS, DATA, DAYS LIVING RADIOISOTOPES, DISEASES, DISPERSIONS, ELECTRON CAPTURE RADIOISOTOPES, GELS, INDIUM ISOTOPES, INFORMATION, INTERMEDIATE MASS NUCLEI, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, MAMMALS, MEDICINE, MINUTES LIVING RADIOISOTOPES, NUCLEI, NUMERICAL DATA, ODD-EVEN NUCLEI, ORGANIC COMPOUNDS, POLYMERS, RADIOISOTOPES, RODENTS, VERTEBRATES
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