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AbstractAbstract
[en] One of the most promising classes of the biomaterials seems to be hydrogels. Hydrogels are hydrophilic polymeric network which may absorb water in the amount from 10% up to thousands of times their dry weight. PVP hydrogel has excellent transparency, compatibility and are widely applied such as wound dressings or drug delivery systems. PVP hydrogel are normally prepared in the presence of PEG as a plasticizer and to modify the gelation and maximum swelling and in the presence of agar to enhance the mechanical properties. It has been reported in various literatures manufacturing of PVP hydrogels using gamma radiation but in this work we use electron beam radiation for crosslinking. Manufacturing of PVP hydrogels via gamma radiation has been reported in various literatures but in this work we use electron beam radiation for crosslinking. The hydrogels were prepared using PVP, PEG and agar. Aqueous solutions of hydrogels components were prepared. Then the homogenous solutions were formed and irradiated under 10 MeV electron beam by Rhodotron accelerator TT200 model in dose range varied from 15 to 40 kGy to become crosslinked. The hydrogels in the final form were transparent sheets of few millimeters. Gel fraction, maximum swelling and mechanical properties of the samples were measured. According to the results, the gel fraction of hydrogels increased with the increasing of the dose and decreased with the increasing of the relative content of PEG in hydrogel. The results show that the maximum swelling increases with increasing of the PEG concentration, which is due to a decrease of the crosslink density. The hydrogels containing PVP and PEG (without gar) were brittle and showed poor mechanical properties. With addition of agar to hydrogels formulation, the mechanical properties increased, immediately. The hydrogel containing 6% PVP, 6% PEG and 3% agar showed the best mechanical properties in 25 kGy
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Source
Hacettepe University, (Turkey); Turkish Atomic Energy Authority, (Turkey); The Scientific and Technological Research Council of Turkey, (Turkey); International Atomic Energy Agency , (Austria); CEA-Saclay, (France); CEA-Saclay Drecam, (France); ANKAmall Shopping Center, (Turkey); Ion Beam Applications Industrial, (Belgium); 205 p; 2006; p. 127; IRAP 2006: 7. International Symposium on Ionizing Radiation and Polymers; Antalya (Turkey); 23-28 Sep 2006; Also available from the author by e-mail: mghaffari@yrpc.ir
Record Type
Miscellaneous
Literature Type
Conference; Numerical Data
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ALCOHOLS, AMIDES, AZOLES, BEAMS, BLOOD SUBSTITUTES, CARBOHYDRATES, CHEMICAL REACTIONS, COLLOIDS, DATA, DEFORMATION, DISPERSIONS, DRUGS, ELECTROMAGNETIC RADIATION, GELS, GLYCOLS, HEMATOLOGIC AGENTS, HETEROCYCLIC COMPOUNDS, HYDROXY COMPOUNDS, INFORMATION, IONIZING RADIATIONS, LACTAMS, LEPTON BEAMS, NUMERICAL DATA, ORGANIC COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, ORGANIC POLYMERS, PARTICLE BEAMS, POLISHING, POLYMERIZATION, POLYMERS, POLYSACCHARIDES, POLYVINYLS, PYRROLES, PYRROLIDONES, RADIATIONS, SACCHARIDES, SURFACE FINISHING
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