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AbstractAbstract
[en] Objective: To evaluate the treatment effect of stereotactic radiotherapy (SBT) in combination with chemotherapy for rectal cancer of postoperative local recurrence. Methods: Sixty-one rectal cancer cases of postoperative local recurrence were treated with conventional radiotherapy plus 3D-CRT (44 Gy/22 Fx + 15-21 Gy/5-7 Fx) in combination with chemotherapy (5-Fu 0.75 + CF 200 mg for days 1-5 and days 29-33; Cisplatin 40 mg for days 1-3 and days 29-31). Acute and late radiation syndrome and survival rates were observed, and survival analysis was carried out using Kaplan-Meier method. Results: The local control rates were 86.9%, 67.2%, and 37.7%, for the first, second and the third years, respectively. Its corresponding survival rates and tumor-free survival rates in each year were estimated to be 80.3%, 62.3%, 39.2%, and 79.7%, 52.5%, and 31.1%, respectively. The median survival time was estimated to be 24.6 months. Acute radiation syndrome including enterititis, rectitis, and urocystitis were observed, and its degree varied from grade 1 to grade 2. Conclusion: Conventional radiotherapy plus three dimensionally radiotherapy in combination with chemotherapy could be considered as an effective and feasible treatment for cancer patients of postoperative local recurrence. (authors)
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11 refs.
Record Type
Journal Article
Journal
Chinese Journal of Radiological Medicine and Protection; ISSN 0254-5098;
; v. 26(3); p. 251-253

Country of publication
AMINO ACIDS, ANTIMETABOLITES, AROMATICS, AZAARENES, AZINES, BIOLOGICAL EFFECTS, BIOLOGICAL RADIATION EFFECTS, BODY, CARBOXYLIC ACIDS, COMPLEXES, DIGESTIVE SYSTEM, DISEASES, DRUGS, GASTROINTESTINAL TRACT, HEMATINICS, HEMATOLOGIC AGENTS, HETEROCYCLIC COMPOUNDS, HYDROXY COMPOUNDS, INJURIES, INTESTINES, LARGE INTESTINE, MEDICINE, NEOPLASMS, NUCLEAR MEDICINE, ORGANIC ACIDS, ORGANIC COMPOUNDS, ORGANIC FLUORINE COMPOUNDS, ORGANIC HALOGEN COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, ORGANS, PATHOLOGICAL CHANGES, PTERIDINES, PYRIMIDINES, RADIATION EFFECTS, RADIOLOGY, SYMPTOMS, THERAPY, TRANSITION ELEMENT COMPLEXES, URACILS, URINARY TRACT, VITAMIN B GROUP, VITAMINS
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